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ACER1 Antikörper (C-Term)

Dieser Anti-ACER1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ACER1 in WB. Geeignet für Human, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund und Schwein.
Produktnummer ABIN2788591

Kurzübersicht für ACER1 Antikörper (C-Term) (ABIN2788591)

Target

Alle ACER1 Antikörper anzeigen
ACER1 (Alkaline Ceramidase 1 (ACER1))

Reaktivität

Human, Ratte, Rind (Kuh), Meerschweinchen, Kaninchen, Hund, Schwein

Wirt

  • 17
Kaninchen

Klonalität

  • 17
Polyklonal

Konjugat

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ACER1 Antikörper ist unkonjugiert

Applikation

  • 15
  • 12
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    VNAYALNSIA LHILYIVCQE YRKTSNKELR HLIEVSVVLW AVALTSWISD

    Homologie

    Cow: 79%, Dog: 92%, Guinea Pig: 75%, Human: 100%, Pig: 85%, Rabbit: 86%, Rat: 77%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ACER1. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the C terminal region of human ACER1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 264 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    ACER1 (Alkaline Ceramidase 1 (ACER1))

    Andere Bezeichnung

    ACER1

    Hintergrund

    ACER1 hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 8.0. It has a highly restricted substrate specificity for the natural stereoisomer of ceramide with D-erythro-sphingosine but not D-ribo-phytosphingosine or D-erythro-dihydrosphingosine as a backbone. It may have a role in regulating the levels of bioactive lipids ceramide and sphingosine 1-phosphate, as well as complex sphingolipids.
    Alias Symbols: ASAH3, MGC138327, MGC138329, ALKCDase1
    Protein Size: 264

    Molekulargewicht

    31 kDa

    Gen-ID

    125981

    NCBI Accession

    NM_133492, NP_597999

    UniProt

    Q8TDN7
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